Epigenetic control of differentiation of mesenchymal stem cells. Stem cells differentiation in liver
https://doi.org/10.29235/1029-8940-2020-65-1-106-118
Abstract
The recent data on epigenetic control of differentiation in mesenchymal stem cells to be the background of embryogenesis and regeneration process in organism are considered. Epigenetic control is bases on three intramolecular mechanisms – DNA methylation, structural modification of histone proteins and microRNA active on posttranscription and posttranslation levels. As an example, the issues of stem cell differentiation in the liver are considered.
About the Authors
I. D. Volotovski
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
Igor D. Volotovski – Academician, D. Sc. (Biol.), Head of the Labоratory
27, Akademicheskaya Str., 220072, Minsk
D. A. Ermolenko
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
Darya A. Ermolenko – Junior researcher
27, Akademicheskaya Str., 220072, Minsk
N. I. Harokhava
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
Nadezhda I. Harokhava – Junior researcher
27, Akademicheskaya Str., 220072, Minsk
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