ANALYSIS OF THE CYTOKINES EXPRESSION IN IMMUNIZATION VACCINE-INACTIVATED CALF BY MEANS “BELVIROPAST”
Abstract
The screening of the structural proteins of pathogenic bacteria and analysis of gene expression markers of the immune response of lymphocytes of animals in the presence of inactivated vaccine for prophylaxis of bovine infectious rhinotracheitis, bovine viral diarrhea, parainfluenza-3 and pasteurellosis of cattle “BelViroPastˮ was carried out. It was shown that vaccination causes activation of the immune system of the animal, as evidenced by an increase in the level of expression of genes that regulate the immune response. The findings are proof that the developed vaccine may be used for specific prevention viral and bacterial respiratory diseases of calves.
About the Authors
L. A. Baranova
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
I. D. Volotovski
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
D. S. Borysovets
S. N. Vyshelesski Institute of Experimental Veterinary
Belarus
Belarus
P. A. Krasochko
S. N. Vyshelesski Institute of Experimental Veterinary
Belarus
Belarus
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