CREATION OF STRAIN PRODUCING SPECIES-SPECIFIC INTERFERON-ALPHA FOR DEVELOPMENT OF ANTIVIRAL PREPARATIONS FOR SHEEPS
Abstract
Infectious diseases became a serious problem for sheep breeding, leading to significant economic losses. The aim of this study: to examine the feasibility of using recombinant interferons as a basis for development of antiviral preparations for sheeps. With reference to comparative analysis of IFN amino acid sequences we can suppose, that neither of the existing IFNbased veterinary preparations is suitable for therapy of ovine viral diseases. Also during this work, synthesized sequence of ovine interferon-α1 gene was cloned in Escherichia coli cells.
About the Authors
K. V. Vostrykava
Belarusian State University
Belarus
Postgraduate student
Belarus
Postgraduate student
S. G. Golenchenko
Belarusian State University
Belarus
Researcher
Belarus
Researcher
M. I. Patapovich
Belarusian State University
Belarus
Head of Laboratory
Belarus
Head of Laboratory
U. A. Prakulevich
Belarusian State University
Belarus
D. Sc. (Biol.), Professor, Head of Department
Belarus
D. Sc. (Biol.), Professor, Head of Department
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