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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestib</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Национальной  академии наук Беларуси. Серия биологических наук</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the National Academy of Sciences of Belarus, Biological Series</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1029-8940</issn><issn pub-type="epub">2524-230X</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestib-71</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Оценка ассоциации полиморфных генов соматотропинового каскада с уровнем продуктивности крупного рогатого скота</article-title><trans-title-group xml:lang="en"><trans-title>Evaluation of polymorphic gene association of somatotropin cascade with cattle productivity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белая</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Belaya</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">L.Belaya@igc.bas-net.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailava</surname><given-names>M. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Институт генетики и цитологии НАН Беларуси</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>07</day><month>06</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>36</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белая Е.В., Михайлова М.Е., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Белая Е.В., Михайлова М.Е.</copyright-holder><copyright-holder xml:lang="en">Belaya E.V., Mikhailava M.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestibio.belnauka.by/jour/article/view/71">https://vestibio.belnauka.by/jour/article/view/71</self-uri><abstract><p>В качестве потенциальных генетических маркеров молочной продуктивности у крупного рогатого скота белорусской чернопестрой и голштинской пород исследовано шесть однонуклеотидных замен, локализованных в ключевых генах соматотропинового каскада: bPit-1-HinFI, bPit-1StuI, bPRL- RsaI, bGH-AluI, bGHR-SspI и bIGF-1-SnaBI. Показано, что при оценке ассоциации полиморфизма с признаком целесообразно проводить оценку фенотипического эффекта предпочтительного и нежелательного генотипов по отношению к уровню продуктивности общей выборки.</p></abstract><trans-abstract xml:lang="en"><p>As potential genetic markers of milk productivity traits in cattle of Holstein and Black-and-white breeds were studied six single nucleotide replacements, situated in key gene of somatotropin cascade: bPit-1-HinFI, bPit-1StuI, bPRL- Rsal, bGH-AluI, bGHR-Sspl and bIGF-1-SnaBI. Was shown that in time of evaluation of polymorphism association with a sign, it is expedient to carry out the evaluation of phenotypic effect of preferable and undesirable genotypes in relation to the level of general selection productivity.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vlaic A., Edriss V. A., Rahmani H. 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