vestibИзвестия Национальной академии наук Беларуси. Серия биологических наукProceedings of the National Academy of Sciences of Belarus, Biological Series1029-89402524-230XThe Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"10.29235/1029-8940-2020-65-1-71-75vestib-650Research ArticleСтатьиЛокализация и состав кумаринов в корнях борщевика Сосновского (Heracleum sosnowskyi Manden.)Localization and composition of coumarins in roots of Heracleum sosnowskyi Manden.ЛаманН. А.LamanN. A.

Ламан Николай Афанасьевич – академик, д-р биол. наук, профессор, заведующий лабораторией

ул. Академическая, 27, 220072, г. Минск

Nikolai A. Laman – Academician, D. Sc. (Biol.), Professor, Head of the Laboratory

27, Akademicheskaya Str., 220072, Minsk

nikolai.laman@gmail.comУсикА. В.UsikA. W.

Усик Анастасия Викторовна – аспирант, мл. науч. сотрудник

ул. Академическая, 27, 220072, г. Минск

Anastasia W. Usik – Postgraduate student, Junior researcher

27, Akademicheskaya Str., 220072, Minsk

jalja-93@mail.ruИнститут экспериментальной ботаники им. В. Ф. Купревича НАН БеларусиV. F. Kuprevich Institute of Experimental Botany of the National Academy of Sciences of Belarus2020110220206517175Copyright © Ламан Н.А., Усик А.В., 20202020Ламан Н.А., Усик А.В.Laman N.A., Usik A.W.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestibio.belnauka.by/jour/article/view/650

В статье представлены результаты исследования локализации кумариновых соединений в подземных органах борщевика Сосновского (Heracleum sоsnowskyi Manden.). Установлено, что кумариновые соединения накапливаются в виде белого секрета в эндогенных секреторных структурах корней. Хроматографическое разделение содержимого секреторных структур показало наличие в нем четырех веществ фурокумариновой природы: ангелицина, бергаптена, ксантотоксина и псоралена.

There are research results of the localization of coumarins in roots. Coumarins accumulated in the form of a white secret (latex) in the secretory structures of roots. Chromatographic separation of latex showed four furocoumarins in the roots of Heracleum. These are angelicin, bergapten, xanthotoxin and psoralen.

Heracleum sоsnowskyi Manden.борщевик Сосновскогокумариныфурокумаринытонкослойная хроматограммасекреторные вместилищакореньHeracleum sоsnowskyi Manden.coumarinsfurocoumarinsthin layer chromatographysecretory tissuesrootsReferencesКлепов, И. Д. Пузыристые дерматиты от лугового растения борщевика / И. Д. Клепов // Вестн. дерматол. и венерол. – 1960. – Т. 3. – С. 55–56.Klepov I. D. Bubbling dermatitis from a meadow Hogweed plant. Vestnik dermatologii i venerologii [Bulletin of dermatology and venereology], 1960, vol. 3, pp. 55–56 (in Russian).Kasperkiewicz, K. Sunscreening and photosensitizing properties of coumarins and their derivatives / K. Kasperkiewicz, A. Erkiert-Polguj, E. Budzisz // Lett. Drug Design Discovery. – 2016. – Vol. 13, N 5. – P. 465–474. https://doi.org/10.2174/1570180812666150901222106Kasperkiewicz K., Erkiert-Polguj A., Budzisz E. Sunscreening and photosensitizing properties of coumarins and their derivatives. Letters in Drug Design and Discovery, 2016, vol. 13, no. 5, pp. 465–474. https://doi.org/10.2174/1570180812666150901222106Emami, S. Current developments of coumarin-based anti-cancer agents in medicinal chemistry / S. Emami, S. Dadashpour // Eur. J. Med. Chem. – 2015. – Vol. 102. – P. 611–630. https://doi.org/10.1016/j.ejmech.2015.08.033Emami S., Dadashpour S. Current developments of coumarin-based anti-cancer agents in medicinal chemistry. European Journal of Medicinal Chemistry, 2015, vol. 102, pp. 611–630. https://doi.org/10.1016/j.ejmech.2015.08.033Recent developments of C-4 substituted coumarin derivatives as anticancer agents / J. Dandriyal [et al.] // Eur. J. Med. Chem. – 2016. – Vol. 119. – P. 141–168. https://doi.org/10.1016/j.ejmech.2016.03.087Dandriyal J., Singla R., Kumar M., Jaitak V. Recent developments of C-4 substituted coumarin derivatives as anticancer agents. European Journal of Medicinal Chemistry, 2016, vol. 119, pp. 141–168. https://doi.org/10.1016/j.ejmech.2016.03.087Antioxidant activity of coumarins / Y. Al-Majedy [et al.] // System. Rev. Pharm. – 2017. – Vol. 8, N 1. – P. 24–30. https://doi.org/10.5530/srp.2017.1.6Al-Majedy Y., Al-Amiery A., Kadhum A. A., BakarMohamad A. Antioxidant activity of coumarins. Systematic Reviews in Pharmacy, vol. 8, no. 1, pp. 24–30. https://doi.org/10.5530/srp.2017.1.6Recent developments of coumarin-containing derivatives and their anti-tubercular activity / Y. Q. Hu [et al.] // Eur. J. Med. Chem. – 2017. – Vol. 136. – P. 122–130. https://doi.org/10.1016/j.ejmech.2017.05.004Hu Y. Q., Xu Z., Zhang S., Wu X., Ding J. W., Lv Z. S., Feng L. S. Recent developments of coumarin-containing derivatives and their anti-tubercular activity. European Journal of Medicinal Chemistry, 2017, vol. 136, pp. 122–130. https://doi.org/10.1016/j.ejmech.2017.05.004Coumarin derivatives as monoamine oxidase B inhibitors with antiparkinsonian like properties / P. Olaya [et al.] // FarmaJournal. – 2019. – Vol. 4, N 1. – P. 218.Olaya P., Viña D., Lopez J. L., Guerrero M. Coumarin derivatives as monoamine oxidase B inhibitors with antiparkinsonian like properties. FarmaJournal, 2019, vol. 4, no. 1, p. 218.Coumarin: A natural, privileged and versatile scaffold for bioactive compounds / A. Stefanachi [et al.] // Molecules. – 2018. – Vol. 23, N 2. – P. 250. https://doi.org/10.3390/molecules23020250Stefanachi A., Leonetti F., Pisani L., Catto M., Carotti A. Coumarin: a natural, privileged and versatile scaffold for bioactive compounds. Molecules, 2018, vol. 23, no. 2, p. 250. https://doi.org/10.3390/molecules23020250Corsi, G. Secretory Structures and Localization of Alkaloids in Conium maculatum L. (Apiaceae) / G. Corsi, D. Biasci // Ann. Botany. – 1998. – Vol. 81, N 1. – P. 157–162. https://doi.org/10.1006/anbo.1997.0547Corsi G., Biasci D. Secretory structures and localization of alkaloids in Conium maculatum L. (Apiaceae). Annals of Botany, 1998, vol. 81, no. 1, pp. 157–162. https://doi.org/10.1006/anbo.1997.0547Mu, Y. Comparative anatomy on structure and distribution of secretory canals in different organs of Cryptotaenia japonica Hassk. (Apiaceae) / Y. Mu, Q. X. Liu // J. Plant Resources Environment. – 2009. – Vol. 18, N 2. – P. 1–8.Mu Y., Liu Q. X. Comparative anatomy on structure and distribution of secretory canals in different organs of Cryptotaenia japonica Hassk. (Apiaceae). Journal of Plant Resources and Environment, 2009, vol. 18, no. 2, pp. 1–8.A new diagnostic character in the roots of the genus Grammosciadium DC. (Apiaceae) / F. Ulusoy [et al.] // Phytotaxa. – 2016. – Vol. 292, N 2. – P. 150–160. https://doi.org/10.11646/phytotaxa.292.2.2Ulusoy F., İdman D. Ö. M., Karakaya M. A., Bani B. A new diagnostic character in the roots of the genus Grammosciadium DC. (Apiaceae). Phytotaxa, 2016, vol. 292, no. 2, pp. 150–160. https://doi.org/10.11646/phytotaxa.292.2.2Bercu, R. Histoanatomy of vegetative organs with bioactive principles in Apium graveolens L. var. Rapaceum (Mill.) gaud. (Apiaceae) / R. Bercu, M. Fagaras // Ann. West Univ. Timisoara. Biology series. – 2014. – Vol. 17, N 1. – P. 45–48.Bercu R., Fagaras M. Histoanatomy of vegetative organs with bioactive principles in Apium graveolens L. var. Rapaceum (mill.) gaud. (Apiaceae). Annales of West University of Timisoara. Biology series, 2014, vol. 17, no. 1, pp. 45–48.Lux, A. Structural and physiological characteristics of the tap root of Smyrnium perfoliatum L. (Apiaceae) / A. Lux, E. Masarovicova, R. Olah // Structure and Function of Roots : Proc. of the Fourth Int. symp. on structure and function of roots, June 20–26, 1993, Stará Lesná, Slovakia / ed. : F. Baluška [et al.]. – Springer, Dordrecht, 1995. – P. 99–105.Lux A., Masarovicova E., Olah R. Structural and physiological characteristics of the tap root of Smyrnium perfoliatum L. (Apiaceae). Structure and Function of Roots: Proceedings of the Fourth International symposium on structure and function of roots, June 20–26, 1993, Stará Lesná, Slovakia, 1995, pp. 99–105.Манденова, И. П. Борщевик – Heracleum L. / И. П. Манденова // Флора СССР : в 29 т. / гл. ред. В. Л. Комаров. – Ленинград, 1951. – Т. 17. – С. 223–259.Mandenova I. P. A Hogweed – Heracleum L. Flora of the USSR. Vol. 17. Leningrad, 1951, pp. 223–259 (in Russian).Сацыперова, И. Ф. Борщевики флоры СССР – новые кормовые растения: перспективы использования в народном хозяйстве / И. Ф. Сацыперова. – Ленинград : Наука, 1984. – 218 с.Satsyperova I. F. Hogweeds of the USSR flora – new fodder plants: prospects for use in the national economy. Leningrad, Nauka Publ., 1984. 218 p. (in Russian).Сандина, И. Б. Борщевик Сосновского (Heracleum sоsnowskyi Manden.), его биология и опыт выращивания в Ленинградской области : автореф. дис. ... канд. биол. наук / И. Б. Сандина ; Ботан. ин-т им. В. Л. Комарова. – Л., 1959. – 18 с.Sandina I. B. Hogweed Sosnowski (Heracleum sosnowskyi Manden.), his biology and growing experience in the Leningrad region. Abstract of Ph. D. diss. Leningrad, 1959. 18 p. (in Russian).Шумова, Э. М. Изучение онтогенетического морфогенеза борщевика Сосновского (Heracleum sosnowskyi Manden.) и борщевика Мантегацци (Heracleum mantegazzianum Somm. еt Lev.) в связи с введением в культуру : автореф. дис. ... канд. биол. наук / Э. М. Шумова ; Моск. ордена Ленина и ордена Тр. Кр. Знамени с.-х. акад. им. К. А. Тимирязева. – М., 1970. – 15 с.Shumova E. M. The study of ontogenetic morphogenesis of Sosnovsky hogweed (Heracleum sosnowskyi Manden.) and Mantegazzi hogweed (Heracleum mantegazzianum Somm. et Lev.) in connection with the introduction into the culture. Abstract of Ph. D. diss. Moscow, 1970. 15 p. (in Russian).Бетехтина, А. А. Строение корней свидетельствует о способности Heracleum sosnowsky быстро поглощать ресурсы при оптимальных почвенных условиях / А. А. Бетехтина, А. О. Сергиенко, Д. В. Веселкин // Изв. Рос. акад. наук. Сер. биол. – 2018. – № 3. – С. 281–289.Betekhtina A. A., Sergienko A. O., Veselkin D. V. The root structure indicates the ability of Heracleum sosnowsky to quickly absorb resources under optimal soil conditions. Izvestiya Rossiiskoi akademii nauk. Seriya biologicheskaya [Proceedings of the Russian Academy of Sciences. Biological series], 2018, no. 3, pp. 281–289 (in Russian).Anatomical studies on medicinal part of Heracleum / H. E. Zhao-Ying [et al.] // J. Xihua Teachers College (Natural Science). – 2004. – N 1. – P. 63–67.Zhao-Ying H. E., Qiao-ying Z. H. A. N. G., Yong-hong M. A., An-quan M. I. A. O. Anatomical studies on medicinal part of Heracleum. Journal of Xihua Teachers College (Natural Science), 2004, no. 1, pp. 63–67.Денисова, Г. А. Терпеноидосодержащие структуры растений / Г. А. Денисова. – М. : Наука, 1982. – С. 10–32.Denisova G. A. Structures of terpenoids in plants. Moscow, Nauka Publ., 1982, pp. 10–32 (in Russian).Денисова, Г. А. Методика выделения секрета из эфирномасличных вместилищ растений / Г. А. Денисова // Раст. ресурсы. – 1969. – Т. 5. – С. 458–463.Denisova G. A. Method for secretion isolation from essential oil containers of plants. Rastitel’nye resursy [Plant resources], 1969, vol. 5, pp. 458–463 (in Russian).

The authors declare that there are no conflicts of interest present.