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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestib</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Национальной  академии наук Беларуси. Серия биологических наук</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the National Academy of Sciences of Belarus, Biological Series</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1029-8940</issn><issn pub-type="epub">2524-230X</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestib-199</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Металлотионеины млекопитающих: структура и биологическая роль</article-title><trans-title-group xml:lang="en"><trans-title>Mammalian metallothioneins: structure and biological role</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гармаза</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Harmaza</surname><given-names>Y. M.</given-names></name></name-alternatives><email xlink:type="simple">garmaza@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тамашевский</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tamashevski</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">tayzoe@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слобожанина</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Slobozhanina</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">slobozhanina@ibp.org.by</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт биофизики и клеточной инженерии НАН Беларуси</institution></aff><aff xml:lang="en"><institution>Institute of biophysics and cell engineering of the National Academy of Sciences of Belarus</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>07</day><month>06</month><year>2016</year></pub-date><volume>0</volume><issue>1</issue><fpage>107</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гармаза Ю.М., Тамашевский А.В., Слобожанина Е.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Гармаза Ю.М., Тамашевский А.В., Слобожанина Е.И.</copyright-holder><copyright-holder xml:lang="en">Harmaza Y.M., Tamashevski A.V., Slobozhanina E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestibio.belnauka.by/jour/article/view/199">https://vestibio.belnauka.by/jour/article/view/199</self-uri><abstract><p>. В данном обзоре рассмотрены биологическое значение, структура и функции металлотионеинов, их роль в окислительном стрессе и в индукции программируемой клеточной гибели.</p></abstract><trans-abstract xml:lang="en"><p>+ transport. In this review, the structure and function of metallothioneins, their biological properties, role in oxidative stress and in the induction of programmed cell death are discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>цистеин-обогащенные белки металлотионеины</kwd><kwd>ионы цинка</kwd><kwd>окислительный стресс</kwd><kwd>программируемая клеточная гибель</kwd><kwd>cystein-rich proteins metallothioneins</kwd><kwd>zinc ions</kwd><kwd>oxidative stress</kwd><kwd>programmed cell death</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vasak, M. Metallothioneins: new functional and structural insights / M. Vasak, D. W. Hasler // Curr. Opin. 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