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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestib</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Национальной  академии наук Беларуси. Серия биологических наук</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the National Academy of Sciences of Belarus, Biological Series</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1029-8940</issn><issn pub-type="epub">2524-230X</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestib-183</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Влияние амфотерицина на морфолого-биохимические свойства Penicillium adametzii - продуцента внеклеточной глюкозооксидазы</article-title><trans-title-group xml:lang="en"><trans-title>Effect of amphotericine B on morphological-biochemical properties of Penicillium adametzii - producer of extracellular glucose oxidase</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailova</surname><given-names>R. V.</given-names></name></name-alternatives><email xlink:type="simple">mikhailovarv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семашко</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semashko</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шедько</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shedzko</surname><given-names>H. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демешко</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Demeshko</surname><given-names>O. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобанок</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobanok</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт микробиологии НАН Беларуси</institution></aff><aff xml:lang="en"><institution>Institute of Microbiology of the National Academy of Sciences</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>07</day><month>06</month><year>2016</year></pub-date><volume>0</volume><issue>1</issue><fpage>23</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайлова Р.В., Семашко Т.В., Шедько А.А., Демешко О.Д., Лобанок А.Г., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Михайлова Р.В., Семашко Т.В., Шедько А.А., Демешко О.Д., Лобанок А.Г.</copyright-holder><copyright-holder xml:lang="en">Mikhailova R.V., Semashko T.V., Shedzko H.A., Demeshko O.D., Lobanok A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestibio.belnauka.by/jour/article/view/183">https://vestibio.belnauka.by/jour/article/view/183</self-uri><abstract><p>М) и охарактеризованы морфологические варианты P. adametzii. Повышение уровня синтеза глюкозооксидазы на 12,5-88,2 % при глубинном выращивании отмечено у 4 штаммов P. adametzii А: 2.19, 5.16, 5.17, 5.18. P. adametzii А 5.17 отобран как перспективный продуцент глюкозооксидазы, характеризующийся максимальными значениями уровня образования фермента и продуцирующей способности мицелия.</p></abstract><trans-abstract xml:lang="en"><p>M) and characterized. Enhanced glucose oxidase production (by 12.5-88.2 %) in the course of submerged fermentation was recorded in 4 P. adametzii strains: 2.19; 5.16; 5.17; 5.18. P. adametzii A 5.17 was chosen as the promising glucose oxidase producer distinguished by maximum values of enzyme generation and productive capacity of the mycelium.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>глюкозооксидаза</kwd><kwd>Penicillium adametzii</kwd><kwd>биосинтез</kwd><kwd>стресс-фактор</kwd><kwd>амфотерицин В</kwd><kwd>селекция</kwd><kwd>морфологические варианты</kwd><kwd>Glucose oxidase</kwd><kwd>Penicillium adametzii</kwd><kwd>biosynthesis</kwd><kwd>stress factor</kwd><kwd>amphotericin B</kwd><kwd>selection</kwd><kwd>morphological variants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kouznetsov, A. Ye. Simultaneous hybrid processes as a way to improve characteristics of cultivation of micro-organisms and biodestruction of pollutants / A. Ye. Kouznetsov, S. V. 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